The Cortactin-binding Postsynaptic Density Protein ProSAP1 in Non-neuronal Cells
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چکیده
منابع مشابه
The cortactin-binding postsynaptic density protein proSAP1 in non-neuronal cells.
Proline-rich synapse-associated protein-1 (ProSAP1) is a neuronal PDZ domain-containing protein that has recently been identified as an essential element of the postsynaptic density. Via its interaction with the actin-binding protein cortactin and its integrative function in the organization of neurotransmitter receptors, ProSAP1 is believed to be involved in the linkage of the postsynaptic sig...
متن کاملProline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density.
The postsynaptic density (PSD) is crucially involved in the structural and functional organization of the postsynaptic neurotransmitter reception apparatus. Using antisera against rat brain synaptic junctional protein preparations, we isolated cDNAs coding for proline-rich synapse-associated protein-1 (ProSAP1), a PDZ-domain protein. This protein was found to be identical to the recently descri...
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ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2001
ISSN: 0022-1554,1551-5044
DOI: 10.1177/002215540104900511