THE CORRELATION BETWEEN DEXA SCAN SCORES AND VITAMIN D LEVELS IN ADULTS WITH CYSTIC FIBROSIS

Vitamin D Deficiency in Cystic Fibrosis

Cystic Fibrosis is the most common inherited genetic respiratory disorder in the Western World. Hypovitaminosis D is almost universal in CF patients, likely due to a combination of inadequate absorption, impaired metabolism, and lack of sun exposure. Inadequate levels are associated with the high prevalence of bone disease or osteoporosis in CF patients, which is associated with increased morbi...

Vitamin D and parathyroid hormone and bone mineralisation in adults with cystic fibrosis.

Vitamin D and parathyroid hormone concentrations were assessed in 31 adults with cystic fibrosis (mean age 24, range 17-52 years), in 28 of whom the bone mineral index in the forearm was also determined. Serum 25-hydroxyvitamin D was subnormal in eight patients, of whom five were receiving vitamin D supplements in standard doses. 1,25-dihydroxyvitamin D and parathyroid hormone concentrations sh...

Vitamin D insufficiency in children, adolescents, and young adults with cystic fibrosis despite routine oral supplementation.

BACKGROUND Cystic fibrosis (CF) with pancreatic insufficiency is associated with poor absorption of fat and fat-soluble vitamins, including vitamin D. Pancreatic enzyme supplementation does not completely correct fat malabsorption in CF patients. OBJECTIVE The objective of the study was to compare the vitamin D status of children, adolescents, and young adults with CF who were treated with ro...

Correlation between vitamin D and cardiac natriuretic peptide levels in vitamin D deficient women

Pilot study of vitamin D supplementation in adults with cystic fibrosis pulmonary exacerbation

UNLABELLED BACKGROUND Vitamin D insufficiency is common in cystic fibrosis (CF) and vitamin D repletion may have an important role in improving clinical outcomes in CF. This randomized, placebo-controlled, pilot study examined the feasibility and impact of a single, large dose of cholecalciferol on vitamin D status and clinical outcomes in subjects with CF. METHODS Thirty ...