The Combination of Microneedles with Electroporation and Sonophoresis to Enhance Hydrophilic Macromolecule Skin Penetration
نویسندگان
چکیده
منابع مشابه
The combination of microneedles with electroporation and sonophoresis to enhance hydrophilic macromolecule skin penetration.
The objective of the present work was to investigate the effects of 3 combinatorial techniques (microneedle (MN), electroporation (EP), and sonophoresis (SN)) on the in vitro skin permeation of the hydrophilic macromolecular compound fluorescein isothiocyanate-dextran (FD-4; molecular weight (MW) 4.4 kDa). Assessment of the in vitro skin permeation of FD-4 was performed in porcine skin. MN, EP,...
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Vol. 27, No. 3, 2015 343 Received August 29, 2013, Revised June 26, 2014, Accepted for publication July 20, 2014 Corresponding author: Min Kyung Shin, Department of Dermatology, Kyung Hee University College of Medicine, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-872, Korea. Tel: 82-2-958-8300, Fax: 82-2-969-6538, E-mail: [email protected] This is an Open Access article distributed under the t...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 2014
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.b14-00321