The Clinical Usefulness of Hydrogen Gas as an Indicator of Left-to-Right Shunts

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The Clinical Usefulness of Hydrogen Gas as an Indicator of Left-to-right Shunts.

SEVERAL indicators have been recommended for the detection of intracardiae left-to-right shunts. The complexity of in-strumentation, the difficulties in handling radioactive materials, and the time involved in the sampling required have precluded the general acceptance of any one method as a routine screening procedure. Furthermore, oxygen saturations, as well as methods utilizing radiopaque co...

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Experience with Hydrogen as an Indicator of Left-to-right Shunts.

Detection of intracardiac shunts by means of conventional oximetry, dye dilution curves, nitrous oxide, or krypton gas tests, may be hampered by lack of sensitivity of the method, cost, or complexity of equipment and unreliability of the results. The hydrogen technique proposed by Clark and Bargeron (1959a, b) and Bargeron, Clark, and McArthur (1960) seems to obviate these disadvantages. The fo...

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Left-to-Right Shunts

Contrary to the opinion of French pediatrician HenriLouis that isolated ventricular septal defects (VSDs) are universally well tolerated, the subsequent discoveries of Eisenmenger, Abbott, Wood, and others have taught us that the prognosis of left-to-right shunt lesions is not always benign. After more than a century of research, as pediatric cardiologists and congenital heart surgeons, we clai...

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The Identification of Right-to-Left Shunts

SEVERAL METHODS are now used in conjunction with cardiac catheterization for localizing and quantitating right-to-left shunts. These include the recording of indicator-dye concentration curves after selective intracardiac dye injection,14 the external recording of radioactivity following injection of radioactive materials,5 6 and the use of cardioangiograms or cineangiograms to picture the cour...

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ژورنال

عنوان ژورنال: Circulation

سال: 1963

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.28.4.542