THE CHRONIC FORM OF MENINGOCOCCUS MENINGITIS

Meningococcus carrier rates and meningitis incidence.

The purpose of this paper is to review certain general features of the epidemiology of meningococcus meningitis in the light of a survey of meningococcus carriage which was carried on continuously from December, 1941, to May, 1945, with a final carrier test in December, 1946. This was part of a survey including hemolytic streptococci, Corynibacterium diphtheriae and Hemophilus influenzae, which...

The Pathogenesis of Meningococcus Meningitis in the Chick Embryo

1. A microscopic and bacteriological analysis of the meningitis produced in the chick embryo following inoculation of meningococci into the body wall or into the amniotic cavity indicates that the meninges are invaded by way of the blood stream. 2. There is no indication that a direct extension of the infection by way of the middle ear, the cranial sinuses or the pia-arachnoid sheath of the olf...

Combined forms of meningitis: Mixed infection of the meninges by the tubercle bacillus and meningococcus.

An Atypical Meningococcus Isolated from Cerebrospinal Fluid in the Calcutta Meningitis Epidemic of 1934-35.

Between the years 1932 and 1935 there were frequent outbreaks of meningitis in an epidemic form in Calcutta and disappointing results were obtained with serum therapy in Calcutta hospitals. The same disappointing results were also reported from the United States of America. Sara Branham of the National Institute of Health, United States Public Health Service, Washington, D. C., took up the stud...

Meningococcus B

Between 13 different serogroups of N. meningitidis, identified according to the capsular polysaccharide’s antigenic structure, only 5 (A, B, C, W-135 and Y) are clinically relevant and responsible for 90% cases of meningococcal invasive disease. In Italy, serogroup B is the principal cause of invasive meningococcal disease [1]. There are two types of tetravalent vaccines for serogroups A, C, W-...