منابع مشابه
The Chemistry of Human Epidermis
Recently information has been presented concerning the close chemical relationship of the proteins of many ectodermal tissues. It has become increasingly clear that the keratins of these structures have a similar molecular pattern and may be tentatively defined as proteins which are resistant to digestion by pepsin and trypsin, which are insoluble in dilute acids, dilute alkalies, water, and in...
متن کاملدر ملانوم بدخیم Consumption of the epidermis
Background and Aim: Consumption of the epidermis (COE) is defined as thinning of the epidermis with attenuation of the basal and suprabasal layers and loss of rete ridges in areas of direct contact with malignant melanocytes. The aim of this study was to investigate the importance of COE as an additional diagnostic criterion for malignant melanoma and to evaluate its relationship to clinicopath...
متن کاملElectron Microscope Studies of the Human Epidermis
The thin skin of the left upper quadrant of the human abdomen has been studied by electron microscopy. Tissue removed with a high speed rotary punch was fixed in osmium tetroxide or potassium permanganate. The latter fixative in our preparations is superior to osmium for the demonstration of epidermal cell membranes and certain other membranous structures of the epidermis. The cytoplasmic membr...
متن کاملMucopolysaccharides in human epidermis.
In a previous publication on the Gram staining material of human epidermis we advanced the theory that keratohyalin contained a highly resistant mucopolysaccharide. In the course of normal keratinization this material was decomposed, while in parakeratotic and many other types of pathologic scales it was retained in the horny layer (1). The evidence presented was indirect: we found that the ext...
متن کاملDesmosomes in Developing Human Epidermis
Desmosomes play important roles in the cell differentiation and morphogenesis of tissues. Studies on animal models have greatly increased our knowledge on epidermal development while reports on human developing skin are rare due to the difficult accessibility to the samples. Although the morphology of periderm cells and the process how the epidermis develops very much resemble each other, the t...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1935
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)74991-0