The brain-derived neurotrophic factor in neuronal plasticity and neuroregeneration: new pharmacological concepts for old and new drugs
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چکیده
منابع مشابه
Brain-derived Neurotrophic Factor (BDNF) A new marker to estimate stress effects on neuronal plasticity
Clinical background Brain-derived Neurotrophic Factor (BDNF) as a growth factor is part to the family of neurotrophins. It is a central mediator of stress effects to the neuronal plasticity and links stress and affective disorders as well as somatic diseases. The neurotrophic functions of BDNF influence the survival of neurons und thereby important functions as learning, memory, appetite and sl...
متن کاملInteractive effect of aerobic training and ginseng supplementation on brain-derived neurotrophic factor in 15-18 years old girls
Background and Objective: Neurotrophins are a family of growth factors that are primarily identified by their ability to protect neuronal survival. The family of neurotrophins consists of 4 proteins, one of which is the brain-derived neurotrophic factor (BDNF). The purpose of the present study was to investigate the effect of 6-week aerobic training and ginseng supplementation on BDNF in 15-18 ...
متن کاملBrain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure.
Neurotrophins are key regulators of neuronal survival and function. Here we show that TrkB, the receptor for brain-derived neurotrophic factor (BDNF), is located at parallel fiber to Purkinje cell (PF/PC) synapses of the cerebellum. To determine the effects of TrkB receptor activation on synapse formation and function, we examined the parallel fiber to Purkinje cell synapses of mice with a targ...
متن کاملa fundamental study of "histiriographic metafiction", and "literary genres", as introduced in "new historical philosophy", and tracing them in the works of julian barnes.
abstract a fundamental study of “historio-graphic metafiction” and “literary genres”, as introduced in “new historical philosophy”, and tracing them in the works of julian barnes having studied the two novels, the porcupine and arthur & george, by julian barnes, the researcher has applied linda hutcheon’s historio-graphic metafictional theories to them. the thesis is divided into five cha...
15 صفحه اولA high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning.
We have investigated a potential mechanism by which a diet, similar in composition to the typical diet of most industrialized western societies rich in saturated fat and refined sugar (HFS), can influence brain structure and function via regulation of neurotrophins. We show that animals that learn a spatial memory task faster have more brain-derived neurotrophic factor (BDNF) mRNA and protein i...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2018
ISSN: 1673-5374
DOI: 10.4103/1673-5374.233438