The blastocyst

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Morphogenesis of the mammalian blastocyst.

The first 4 days of mouse pre-implantation development are characterized by a period of segmentation, including morphogenetic events that are required for the divergence of embryonic and extra-embryonic lineages. These extra-embryonic tissues are essential for the implantation into the maternal uterus and for the development of the foetus. In this review, we first discuss data showing unambiguo...

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Blastocyst development rate impacts outcome in cryopreserved blastocyst transfer cycles.

OBJECTIVE To assess cycle outcome among day 5 and day 6 cryopreserved frozen-thawed blastocyst embryo transfers (FBET). DESIGN Retrospective cohort study. SETTING Military-based assisted reproduction technology (ART) center. PATIENT(S) One hundred seventy-two nondonor, programmed cryopreserved embryo cycles. INTERVENTION(S) Fully expanded blastocysts on day 5 were cryopreserved on day 5...

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Making the blastocyst: lessons from the mouse.

Mammalian preimplantation development, which is the period extending from fertilization to implantation, results in the formation of a blastocyst with three distinct cell lineages. Only one of these lineages, the epiblast, contributes to the embryo itself, while the other two lineages, the trophectoderm and the primitive endoderm, become extra-embryonic tissues. Significant gains have been made...

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On the orientation of the implanting blastocyst.

In viviparous mammals the implanting blastocyst is positioned according to a number of parameters which are species specific. First, in polytocous animals the blastocysts become spaced out along the length of the uterus, secondly they take up a particular relationship to the circumference of the endometrium, and lastly the embryonic pole always assumes a constant orientation to the mesometrial-...

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Regulation of blastocyst formation.

Preimplantation or pre-attachment development encompasses the "free"-living period of mammalian embryogenesis, which directs development of the zygote through to the blastocyst stage. Blastocyst formation is essential for implantation, establishment of pregnancy and is a principal determinant of embryo quality prior to embryo transfer. Cavitation (blastocyst formation) is driven by the expressi...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2000

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/15.suppl_4.49