The Association of Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor 2 with Prognosis of Colorectal Cancer under FOLFOX Chemotherapy

To clarify association of epidermal growth factor receptor, human receptor 2 with prognosis colorectal cancer under FOLFOX chemotherapy. A total 108 patients chemotherapy in the hospital from October 2017 to 2019 were chosen as research subjects. The baseline data recorded before treatment and levels serum tumor markers carcino embryonic antigen carbohydrate 125 measured recorded. After 6 courses chemotherapy, was observed. effective included good group remaining ones poor group. laboratory indicators assessed between two groups evaluated. Among completing 18 (16.67 %) had complete response, 29 (26.85 partial 37 (34.26 stable disease 24 (22.22 progressive 56.48 % (61/108) prognosis. Carcino antigen, 125, presented elevation relative those group, statistical significance (p<0.05). Logistic regression analysis demonstrated that (odds ratio >1, p<0.05). receiver operating curve area alone combination predict 0.709, 0.766 0.828, respectively, all which certain predictive value. up regulation may be a risk for unfavourable can used predicting