The association of 5HT2A and 5HTTLPR polymorphisms with Alzheimer’s disease susceptibility: a meta-analysis with 6945 subjects

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The association of 5HT2A and 5HTTLPR polymorphisms with Alzheimer’s disease susceptibility: a meta-analysis with 6945 subjects

Alzheimer's disease (AD) is a progressive neurodegenerative disease. Relationships of 5HT2A and 5HTTLPR polymorphisms and AD risk have been widely investigated previously, whereas results derived from these studies were inconclusive and controversial. The aim of this study was to investigate the association of the 5-HT2A and 5HTTLPR polymorphisms and AD using a meta-analysis of existing literat...

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Background and Aim: Several investigations have evaluated the association of miR-146a rs2910164 and miR-27a rs895819 single-nucleotide polymorphisms with susceptibility to type 2 diabetes (T2D). However, the findings are conflicting and inconclusive. Therefore, this meta-analysis performed to investigate the association between these polymorphisms and T2D risk. Methods: Studies were identifie...

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BACKGROUND The survivin polymorphisms have been shown to confer genetic susceptibility to various tumors, but the results are inconsistent. In order to accomplish a more precise estimation of the relationship, a meta-analysis was performed. RESULTS For rs9904341, a significantly increased tumor risk was found in overall meta-analysis under C/C vs. G/G (OR = 1.40, 95% CI = 1.13-1.74, p = 0.002...

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association between fen1 polymorphisms -69g>a and 4150g>t with susceptibility in human disease: a meta-analysis

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2017

ISSN: 1949-2553

DOI: 10.18632/oncotarget.23611