The Arrestin Fold: Variations on a Theme

The Arrestin Fold: Variations on a Theme

Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. beta-arrestins interact with the phosphorylated tail of activated receptors and act as scaffolds for the recruitment of adaptor proteins and clathrin, that constitute the machinery used for receptor endocytosis. Visual- and beta-arrestins have a two-lobe, immun...

Variations on a theme.

A ring satisfying x = x is necessarily commutative. We consider a variety of weaker forms of this condition and show that many but not all of them imply commutativity. We also present a variety of elementary proofs of the fact that x = x implies commutativity.

Variations on a Theme

Variations on a Montagovian theme

What are the objects of knowledge, belief, probability, apriority or analyticity? For at least some of these properties, it seems plausible that the objects are sentences, or sentence-like entities. However, results from mathematical logic indicate that sentential properties are subject to severe formal limitations. After surveying these results, I argue that they are more problematic than ofte...

The Klein Bottle: Variations on a Theme

It is a well-known fact that K is a genus 2 nonorientable closed surface with Euler characteristic χ = 0, which is topologically equivalent to a couple of Möbius bands glued together along the border, and that it is nonembeddable in R. It is possible, however, to immerse it in R, that is, to map it into R obtaining an image with no singular points. To give an immersion of K in R, it suffices to...