منابع مشابه
Rapid Publication In Vitro Model of Intestinal Crypt Abscess
In order to model crypt abscesses, a histological finding which correlates with disease activity in intestinal inflammation, human polymorphonuclear leukocytes (PMN) were layered onto monolayers of the human intestinal epithelial cell line T84, a crypt-like epithelium which is capable of Clsecretion. Such PMN-epithelial interaction had no substantial effect on monolayer integrity or function. H...
متن کاملCrypt abscess-associated microbiota in inflammatory bowel disease and acute self-limited colitis.
AIM To evaluate whether crypt abscesses from inflammatory bowel disease (IBD) patients contain bacteria and to establish their nature. METHODS We studied 17 ulcerative colitis patients, 11 Crohn's disease patients, 7 patients with acute self-limited colitis (ASLC) and normal colonic biopsies from 5 subjects who underwent colonoscopy for colon cancer screening. A fluorescent in situ hybridizat...
متن کاملSnapShot: The Intestinal Crypt
Intestinal organoids provide a convenient and physiologically relevant in vitro model system to study the intestinal epithelium. This 3D, multicellular culture system recapitulates the lumen and crypt-villus structure of the intestine, and incorporates all of the cell types found in the adult intestinal epithelium. Intestinal organoids make it easier than ever to get in vivo insight from in vit...
متن کاملClub in the Crypt
Youth clubs, like schools, the book says, are open from Monday to Friday, and, like schools, they close in August for holidays, reopening in September. Young people stay at home at weekends, or go away. Fun-seeking. They camp; liven up the West End, Clacton beach, and Margate. If funds are low there is no choice. You stay at home and release your excess boredom and hate on the unsuspecting pass...
متن کاملTales from the crypt
Tales from the crypt ow many stem cells reside in a human colonic crypt and how do they divide and regenerate? According to the deterministic theory, a small number of " immortal " stem cells haunt a crypt, and when they divide, each generates a single replacement stem cell. The stochastic model, in contrast, contends that a crypt niche harbors many stem cells, and each cell division randomly g...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2017
ISSN: 0002-9173,1943-7722
DOI: 10.1093/ajcp/aqx100