The amazing brain drain

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The amazing brain drain

The CNS has long been considered an immune-privileged site as tissues grafted into the CNS are not rejected as they are in other tissues (Medawar, 1948; Billingham and Boswell, 1953; Barker and Billingham, 1977). An avalanche of evidence now suggests that this privilege is not absolute, as robust immune responses can occur in the CNS during infections and autoimmune diseases such as multiple sc...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2017

ISSN: 0022-1007,1540-9538

DOI: 10.1084/jem.20172031