The action of excitatory amino acids on chick spinal cord neurones in culture.
نویسندگان
چکیده
منابع مشابه
Opposing effects of excitatory amino acids on chick embryo spinal cord motoneurons: excitotoxic degeneration or prevention of programmed cell death.
Acute administration of a single dose of NMDA on embryonic day (E) 7 or later induces a marked excitotoxic injury in the chick spinal cord, including massive necrotic motoneuron (MN) death. When the same treatment was performed before E7, little, if any, excitotoxic response was observed. Chronic treatment with NMDA starting on E5 prevents the excitotoxic response produced by a later "acute" ad...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1987
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1987.sp016542