The action of bee venom, cobra venom and lysolecithin on the adrenal medulla
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چکیده
منابع مشابه
Possible mechanisms of action of cobra snake venom cardiotoxins and bee venom melittin.
Cobra snake venom cardiotoxins and bee venom melittin share a number of pharmacological properties in intact tissues including hemolysis, cytolysis, contractures of muscle, membrane depolarization and activation of tissue phospholipase C and, to a far lesser extent, an arachidonic acid-associated phospholipase A2. The toxins have also been demonstrated to open the Ca2+ release channel (ryanodin...
متن کاملCobra Venom Factor and Ketoprofen Abolish the Antitumor Effect of Nerve Growth Factor from Cobra Venom
We showed recently that nerve growth factor (NGF) from cobra venom inhibited the growth of Ehrlich ascites carcinoma (EAC) inoculated subcutaneously in mice. Here, we studied the influence of anti-complementary cobra venom factor (CVF) and the non-steroidal anti-inflammatory drug ketoprofen on the antitumor NGF effect, as well as on NGF-induced changes in EAC histological patterns, the activity...
متن کاملCobra Venom-induced Hemolysis
Interest in the alternate or C3 shunt complement pathway has recently been generated by a number of reports (1-5). Its presence in invertebrates points to a primitive phylogenetic appearance (6). The C3 shunt can be triggered by high molecular weight polysaccharides in a manner reminiscent of the properdin system (7). Once activated by cobra venom, erythrocytes and other cells can be lysed in t...
متن کاملCobra Venom in Therapeutics
During the past eight years the senior author has been engaged in testing the pharmacological action and therapeutic properties of Indian snake venoms. Chopra and Chowhan (1932 and 1935) showed that the efficacy of the cobra and other snake venoms in relieving the pain of malignant growths and of neuritis and neuralgias was probably due to the presence of such active principles as neurotoxin. The
متن کاملThe Effects of Bee Venom
Under the above title Dr. A. R. D'Abreau has an article in the Indian Medical Gazette for November 1926, and as a few very striking cases have come under my personal observation, I am publishing this note. The species generally credited with evil effects is Apis mellifica. L. Brant and Ratzeburg were the first to study bee venom in 1833. Paul Bert in 1865 and Carlet in 1884 also studied it, but...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1940
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1940.sp003883