The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

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The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

AIMS Atrial fibrillation (AF) is associated with an increased risk of stroke, which is currently estimated by clinical characteristics. The cardiac biomarkers N-terminal fragment B-type natriuretic peptide (NT-proBNP) and cardiac troponin high-sensitivity (cTn-hs) are independently associated with risk of stroke in AF. Our objective was to develop and validate a new biomarker-based risk score t...

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A biomarker-based risk score to predict death in patients with atrial fibrillation: the ABC (age, biomarkers, clinical history) death risk score

Aims In atrial fibrillation (AF), mortality remains high despite effective anticoagulation. A model predicting the risk of death in these patients is currently not available. We developed and validated a risk score for death in anticoagulated patients with AF including both clinical information and biomarkers. Methods and results The new risk score was developed and internally validated in 14...

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A New Risk Scheme to Predict Ischemic Stroke and Other Thromboembolism in Atrial Fibrillation: The ATRIA Study Stroke Risk Score

BACKGROUND More accurate and reliable stroke risk prediction tools are needed to optimize anticoagulation decision making in patients with atrial fibrillation (AF). We developed a new AF stroke prediction model using the original Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA) AF cohort and externally validated the score in a separate, contemporary, community-based inception AF ...

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The CHADS2 score for stroke risk stratification in atrial fibrillation--friend or foe?

The risk of stroke in patients with non-valvular atrial fibrillation (NVAF) varies widely depending on patient age and the presence of other risk factors such as hypertension, diabetes mellitus, congestive heart failure or prior stroke or transient ischaemic attack (TIA) (1, 2). Warfarin reduces the risk of stroke by about twothirds when compared to placebo or no treatment, and by about two-fif...

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Which score should be used for risk stratification of ischemic stroke in patients with atrial fibrillation.

is the most important for managing AF. The ACCF/AHA guidelines in the USA,3 the CCS guidelines in Canada,4 and the JCS guidelines in Japan5 recommend using the conventional stroke risk stratification scheme, the CHADS2 (congestive heart failure, hypertension, age >75 years, diabetes mellitus, and stroke [double]) score, for antithrombotic therapy in patients with nonvalvular AF.6 On the other h...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2016

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/ehw054