The 2DG-neutral red test for completeness of vagotomy

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The 2DG-neutral red test for completeness of vagotomy.

Ever since vagotomy became an important part of modern peptic ulcer surgery, investigators have searched for a test that would reliably indicate the completeness of vagus nerve section. The insulin hypoglycemia test, originally advocated by Hollander [8], has remained the most widely utilized test for the completeness of vagotomy, but despite several modifications it’s reliability has been ques...

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The 2-deoxy-D-glucose-neutral red test and vagotomy: an experimental study.

The 2-deoxy-D-glucose - neutral red test proved to be successful in assessing completeness of vagotomy in the baboon both intra- and postoperatively. There were no deleterious side-effects and we found that both products could be sterilized adequately. So far we have used this test of 5 patients in the immediate postoperative phase; in 1 patients, on whom the surgeon thought he had done an inco...

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Use of 2 deoxy-D-glucose to test for the completeness of surgical vagotomy.

A synthetic analogue of glucose, 2-deoxy-D-glucose (2-DG), stimulates vagal hypothalamic centres by lowering intracellular glucose levels. This substance has been used to elicit the vagal phase of gastric secretion in the rat, dog, and man (Baume, Nicholls, Barnett, and Room, 1966; Hirschowitz and Sachs, 1965; Duke, Hirschowitz, and Sachs, 1965). The acid response to 2-DG is equal to that produ...

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ژورنال

عنوان ژورنال: Journal of Surgical Research

سال: 1975

ISSN: 0022-4804

DOI: 10.1016/0022-4804(75)90123-7