The 2019 MTT-S Graduate Student Fellowship Awards [Education News]

Predoctoral Fellowship Awards 2017

EACR Travel Fellowship Awards

Rabs are initially synthesized as soluble proteins; for membrane attachment they require a posttranslational C20-prenylation. Rab GTPases are localized to the cytosolic face of the limiting membrane of organelles, where they function as regulators of distinct steps in membrane trafficking pathways. Rabs cycle between a GTP-bound active and a GDPbound inactive form, assisted by GEFs (guanine nuc...

EACR Travel Fellowship Awards

A key characteristic of malignant cancers is the ability to overcome microenvironmental controls by host, invade tissue, and reach distant sites of the body to form metastases. Cancer cells can induce profound changes in the neighbouring tissue, which in turn provides an environment that favours local tumour growth, metastatic spreading, and contributes to drug response. The host microenvironme...

EACR Travel Fellowship Awards

Prostate cancer as well as other solid cancers are embedded in and supported by the surrounding tumour microenvironment, which usually consists of fibroblasts, smooth muscle cells, endothelial cells and immune cells. In the prostate, fibroblasts and smooth muscle cells represent the bulk of the stroma in both normal and malignant conditions. In carcinomas, there are also pro-tumourigenic cancer...

EACR Travel Fellowship Awards

GSAO (4-(N-(S-glutathionylacetyl)amino) phenylarsonous acid) is a novel organoarsenical compound presently completing phase I trials in cancer patients who are refractory to treatment. GSAO targets the mitochondria of proliferating endothelial cells by binding to calcium-replete adenine nucleotide translocase on the inner mitochondrial membrane. Consequently, small solutes equilibrate across th...