The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane
نویسندگان
چکیده
منابع مشابه
The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.
Atg8 is conjugated to phosphatidylethanolamine (PE) by ubiquitin-like conjugation reactions. Atg8 has at least two functions in autophagy: membrane biogenesis and target recognition. Regulation of PE conjugation and deconjugation of Atg8 is crucial for these functions in which Atg4 has a critical function by both processing Atg8 precursors and deconjugating Atg8-PE. Here, we report the crystal ...
متن کاملon translation of phatic communion and socio-cultural relationships between the characters of the novels
phatic communion is a cultural concept which differs across cultures. according to hofstede (2001), the u.s. tends to have individualistic culture; however, asian countries tend to have collectivistic cultures. these cultures view phatic communion differently. in individualistic cultures like u.s., phatic communion reflects speakers’ socio-cultural relationships in conversations. to see whether...
15 صفحه اولElucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins
Autophagy is a conserved cellular process involved in the elimination of proteins and organelles. It is also used to combat infection with pathogenic microbes. The intracellular pathogen Legionella pneumophila manipulates autophagy by delivering the effector protein RavZ to deconjugate Atg8/LC3 proteins coupled to phosphatidylethanolamine (PE) on autophagosomal membranes. To understand how RavZ...
متن کاملthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
on the relationship between the knowledge of collocations and writing proficiency
بررسی رابطه دانش همنشینی لغات و مهارت نوشتاری در زبان انگلیسی چکیده این پژوهش درصدد آن است تا سه مسئله زیر را مورد بررسی قرار دهد: الف) وجود یا عدم وجود رابطه بین دانش زبان آموزان در حوزه همنشینی لغات با یکدیگر و دانش آنها در مهارت نوشتاری زبان انگلیسی؛ ب) یافتن پاسخی به این سوال که آیا تمامی انواع همنشینی های لغوی زبان انگلیسی به یک میزان برای زبان آموزان دشوارند یا خیر؛ پ) مقایسه زبان آمو...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Autophagy
سال: 2016
ISSN: 1554-8627,1554-8635
DOI: 10.1080/15548627.2016.1243199