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New extraction method of THC and its metabolites, 11-OH-THC and THC-COOH, in plasma
Objectives: A liquid/liquid extraction technique on solid support of Δ9-tetradydrocannabinol (THC), 11-hydroxy-Δ9-tetradydrocannabinol (11-OH-THC) and 11-nor-Δ9-tetradydrocannabinol-9-carboxylic acid (THCCOOH) in plasma was developed in order to be assayed by high-performance liquid chromatography and tandem mass spectrometry (HPLC-MS/MS). Methods: The samples were extracted by liquid/liquid ex...
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ژورنال
عنوان ژورنال: Nature Medicine
سال: 2004
ISSN: 1078-8956,1546-170X
DOI: 10.1038/nm0104-19