Th1 and Th2 cells in autoimmunity

Th1 and Th2 Cytokine Profiles in Malignant Pleural Effusion

Background: The alteration of Th1 and Th2 cytokine levels is the subject of controversy in pleural effusions caused by malignancy, a situation that favors a Th2 immune response. Objective: To examine the different levels of IL-4 and IL-10 (Th2 cytokines), and IL-2 and interferon-γ (IFN-γ) (Th1 cytokines) in malignant and non-malignant pleural effusions. Method: The cytokine levels in pleural fl...

P169: The Role of Lymphocytes in Spinal Cord Injury and Pain; T Helper Cells (TH1 and TH2 Cells)

Lymphocyte is one of the subtypes of white blood cell (WBC) in immune system. Lymphocytes contain T cells, natural killer cells , and B cells. They are the head type of cell found in lymph, which for this reason the name "lymphocyte". Lymphocytes can be recognized by their large nucleus. Infiltration of immune cells in the central nervous system (CNS) helps the start of chronic pain. ...

Antigen-Specific Th1 But Not Th2 Cells

th1/th2 cytokines in psoriasis

background: the aim of this study was to determine the th1 and th2 serum cytokines, in patients with psoriasis and to com pare their cytokine levels with those of normal control subjects. methods: serum levels of interferon-gamma (ifn-γ), interleukin-2 (il-2), interleukin-4 (il-4), and interleukin-10 (il-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in...

Expression of Th1 and Th2 Cytokine and Associated Transcription Factors in Peripheral Blood Mononuclear Cells and Correlation with Disease Severity

Background: Psoriasis is a T cell-mediated autoimmune disease with elevated level of pro-inflammatory cytokines belonging mainly to Th1 pathway. We investigated whether treatment with micronutrients along with methotrexate (MTX) is able to modulate mRNA expression of Th1 and Th2 patterns and its correlation with disease severity. Methods: Thirty plaque type psoriasis patients with Psoriasis ...