TGF-β Enhanced IL-21-Induced Differentiation of Human IL-21-Producing CD4+ T Cells via Smad3
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چکیده
منابع مشابه
TGF-β Enhanced IL-21-Induced Differentiation of Human IL-21-Producing CD4+ T Cells via Smad3
IL-21 has pleiotropic effects on innate and adaptive immune response, and plays an important role in the development of autoimmune disease and antitumor activity. It has been reported that IL-21 is produced by CD4(+) T cells and NKT cells. However, the differentiation of IL-21-producing CD4(+) T cells in humans remains largely unclear. In the present study, we showed that cytokines of IL-1β, IL...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0064612