TGF-beta-dependent and -independent roles of STRAP in cancer
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چکیده
منابع مشابه
TGF-beta-dependent and -independent roles of STRAP in cancer.
The serine-threonine kinase receptor-associated protein (STRAP) was initially identified as a putative inhibitor of the canonical TGF-beta signaling pathway. Because the Smad-dependent TGF-beta pathway negatively regulates cellular growth, early functional studies suggested that STRAP behaves as an oncogene. Indeed, a correlation between STRAP overexpression and various cancers has been identif...
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ژورنال
عنوان ژورنال: Frontiers in Bioscience
سال: 2011
ISSN: 1093-9946,1093-4715
DOI: 10.2741/3678