Testing minimal clinically important difference: additional comments and scientific reality testing

Minimal clinically important difference module: summary, recommendations, and research agenda.

Minimal clinically important difference: defining what really matters to patients.

When assessing the clinical utility of therapies intended to improve subjective outcomes, the amount of improvement that is important to patients must be determined.1 The smallest benefit of value to patients is called the minimal clinically important difference (MCID). The MCID is a patient-centered concept, capturing both the magnitude of the improvement and also the value patients place on t...

Pre-discharge defibrillation testing: clinically important or obsolete?

One of the most controversial and hotly debated topics in implantable cardioverter-defibrillator (ICD) management is the role of defibrillation testing. As with most areas of clinical controversy, the lack of controlled studies to guide the decision process is largely responsible for the ongoing differences in opinion. In the early period of ICD use, defibrillation testing was mandatory given t...

Responsiveness and minimal clinically important difference for pain and disability instruments in low back pain patients

BACKGROUND The choice of an evaluative instrument has been hampered by the lack of head-to-head comparisons of responsiveness and the minimal clinically important difference (MCID) in subpopulations of low back pain (LBP). The objective of this study was to concurrently compare responsiveness and MCID for commonly used pain scales and functional instruments in four subpopulations of LBP patient...

The Patient‐Oriented Eczema Measure in young children: responsiveness and minimal clinically important difference

BACKGROUND The Patient-Oriented Eczema Measure (POEM) has been recommended as the core patient-reported outcome measure for trials of eczema treatments. Using data from the Choice of Moisturiser for Eczema Treatment randomized feasibility study, we assess the responsiveness to change and determine the minimal clinically important difference (MCID) of the POEM in young children with eczema. ME...