Testicular Function after Combined Chemotherapy for Metastatic Testicular Cancer
نویسندگان
چکیده
منابع مشابه
Testicular function following chemotherapy.
Testicular dysfunction is a common long-term sequela of cytotoxic chemotherapy used in the treatment of many malignancies. The degree to which testicular function is affected is dose- and agent-dependent. The impact on germinal epithelial function of standard multi-agent regimens used in the treatment of lymphomas has been widely studied. Procarbazine-containing regimens result in azoospermia i...
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Our initial studies with cisplatin + vinblastine + bleomycin began 27 years ago in 1974, changing the cure rate for disseminated disease from 5 to 60%. Subsequently, through random prospective clinical trials, we have modified the treatment regimen to reduce both the duration and dosages of the chemotherapy drugs. Cisplatin + etoposide was first used at Indiana University as salvage chemotherap...
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She was followed up regularly for almost two years and showed no signs of relapse. She stopped taking antithyroid drugs several times and suffered brief relapses of hyperthyroidism, but without any psychosis. Comment Hyperthyroidism commonly presents with mental changes such as irritability and anxiety, but psychotic symptoms like hallucination and delusion are rare. The review by Ellis and Mel...
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Sarcoidosis is an idiopathic, multisystem disease that rarely involves the genitourinary tract. Here we present an unusual case of testicular sarcoidosis with extensive lymphadenopathy that mimicked a metastatic testicular tumor. A 27-year-old male presented with a palpable right testicular mass accompanied by multiple palpable inguinal lymph nodes. The scrotal ultrasound showed a hypoechoic le...
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Modern chemotherapy combined with surgery can achieve complete cure in over 90% of all patients with malignant testicular germ cell tumors. Even tumors that have already metastasized at the time of orchidectomy are curable by platinum-based multidrug treatment. Chemotherapy related changes can be seen in the residual tumor tissue in metastatic sites. In patients fully responding to chemotherapy...
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ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 1980
ISSN: 0105-6263,1365-2605
DOI: 10.1111/j.1365-2605.1980.tb00095.x