Teratogen update: Fetal effects after in utero exposure to coumarins Overview of cases, follow-up findings, and pathogenesis
نویسندگان
چکیده
منابع مشابه
Teratogen update: fetal effects of indomethacin administration during pregnancy.
Indomethacin is a nonsteroidal anti-inflammatory analgesic used in the treatment of disorders such as rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Prostaglandins have a significant stimulatory effect on established labor; because indomethacin is a potent inhibitor of prostaglandin synthesis, this agent is also used in the treatment of preterm labor. Like other prostaglandin...
متن کاملOne-Year Follow-Up of Radiologic and Clinical Findings in Children with Prenatal and Neonatal Hydronephrosis
Background & Aims: Hydronephrosis is a common problem in prenatal and newborn infants diagnosed by ultrasonography. Bladder to ureter reflux, the upper or lower urinary tract obstruction, and neurogenic bladder are the most common causes of hydronephrosis in newborns and infants. Methods: In this study, 100 neonates and infants with hydronephrosis were observed clinically and laboratorically fo...
متن کاملNystagmus and reduced visual acuity secondary to drug exposure in utero: long-term follow-up.
PURPOSE To investigate nystagmus and other visual system abnormalities among children exposed to opiates and benzodiazepines in utero. METHODS Retrospective case series comprising clinical examination and case note review of 25 children with nystagmus and reduced vision who were exposed to controlled drugs during pregnancy. RESULTS Twenty-four children were exposed to opiates, of whom 13 we...
متن کاملTeratogen update: iodine deficiency, a community teratogen.
In the last decade, iodine deficiency disorders (IDD) have become recognized as the most common preventable cause of mental retardation worldwide. Iodine deficiency interferes severely with prenatal and postnatal growth and neurologic development of individuals. It has condemned tens of millions of children to cretinism—characterized by mental and growth retardation, rigid spastic motor disorde...
متن کاملInvolvement of testicular growth factors in fetal Leydig cell aggregation after exposure to phthalate in utero.
Exposures to di-(2-ethylhexyl) phthalate (DEHP) have been shown to be associated with decreased adult testosterone (T) levels and increased Leydig cell numbers. As yet, little is known about DEHP effects in utero on fetal Leydig cells (FLC). The present study investigated effects of DEHP on FLC function. Pregnant Long-Evans female rats received vehicle (corn oil) or DEHP at 10, 100, or 750 mg/k...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Teratology
سال: 2002
ISSN: 0040-3709,1096-9926
DOI: 10.1002/tera.10054