Tenofovir rescue therapy in chronic hepatitis B patients who failed previous nucleoside analogue treatment
نویسندگان
چکیده
منابع مشابه
Treatment of Chronic Hepatitis B with Tenofovir
Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...
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background tenofovir disoproxil fumarate (tdf) is a new effective treatment option for patients with chronic hepatitis b (chb). objectives to evaluate tdf efficacy in nucleos(t)ide analogues (nas)-naive iranian patients with chb. patients and methods the na-naive patients received tdf for at least six months. the primary endpoint was the proportion of patients achieving a complete virological r...
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Objective (s):The aim of this study was to determine the correlation between vaccine therapy and appearance of mutations in hepatitis B surface antigen (HBsAg)-positive chronic hepatitis B virus (HBV) patients. Materials and Methods: 16 patients received the HBV vaccine and another 16 individuals from the control group did not. The surface gene was amplified and directly sequenced from samples...
متن کاملEfficacy of Tenofovir Disoproxil Fumarate Therapy in Nucleoside-Analogue Naive Iranian Patients Treated for Chronic Hepatitis B
BACKGROUND Tenofovir disoproxil fumarate (TDF) is a new effective treatment option for patients with chronic hepatitis B (CHB). OBJECTIVES To evaluate TDF efficacy in nucleos(t)ide analogues (NAs)-naive Iranian patients with CHB. PATIENTS AND METHODS The NA-naive patients received TDF for at least six months. The primary endpoint was the proportion of patients achieving a complete virologic...
متن کاملIs the tenofovir based therapy almighty for previous treatment failure in chronic hepatitis B?
During the past decade, management of drug resistant chronic hepatitis B (CHB) has been a major issue. A series of new antiviral agents has been developed, which provided new treatment options as well as new resistance issues. Hence, to avoid multidrug resistance, combination of antiviral agents without cross resistance has been recommended. However, combination of the less potent drug did not ...
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ژورنال
عنوان ژورنال: Hepatology International
سال: 2015
ISSN: 1936-0533,1936-0541
DOI: 10.1007/s12072-015-9681-6