Temperature-dependent peptidergic feedback: potential role in seasonal egg laying in Aplysia

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Temperature-dependent peptidergic feedback: potential role in seasonal egg laying in Aplysia.

alpha-Bag cell peptide (alpha-BCP), one of the secretory products of the neuroendocrine bag cells in Aplysia, has been reported by various investigators to have either excitatory or inhibitory feedback effects. Though conflicting, these results may be explained by the difference in temperature at which the experiments were performed. Because egg laying in this animal is temperature dependent, t...

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Nitric oxide induces aspects of egg-laying behavior in Aplysia.

Aplysia egg laying is a complex behavior requiring synchronized activity in many organs. Aspects of the behavior are synchronized via the direct effects of peptide bag cell neurohormones and via stimuli arising during the behavior. Stimuli synchronizing egg laying were examined by treating A. fasciata with a nitric oxide (NO) donor. NO elicited normal appetitive and consummatory behaviors leadi...

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Egg-laying hormone of Aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron.

This report presents studies on ionic currents in Aplysia motoneuron B16 that are modulated by the neuropeptide egg-laying hormone (ELH) of Aplysia. ELH induces an inward current that persists in the presence of the peptide and that decays slowly after ELH is removed from the bath. The effect is not due to a decrease in the delayed potassium current, the calcium-activated potassium current, or ...

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Biochemical isolation and physiological identification of the egg- laying hormone in Aplysia californica

It has been determined that the bag cells of Aplysia californica produce two polypeptide species that comigrate on electrophoretic gels containing sodium dodecyl sulfate. By this separation procedure both species can be assigned a molecular weight of approximately 6,000. One of these molecules has an Rf of 0.65 on alkaline discontinuous electrophoresis gels, an isoelectric point at pH 4.8, a ge...

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Biosynthesis of the Egg-Laying Hormone (ELH) in the Bag Cell Neurons of Aplysia californica

Biosynthesis of the egg-laying hormone in the bag cell neurons of Aplysia californica was studied. Bag cells were incubated with leucine-(3)H in vitro for 30 min and rinsed for variable periods of time in a chase medium. The distribution of incorporated label among proteins within the cells was assayed by electrophoresis of an homogenate on sodium dodecyl sulfate polyacrylamide gels. Results fr...

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 1991

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.11-06-01780.1991