Telomere Rapid Deletion Regulates Telomere Length in Arabidopsis thaliana
نویسندگان
چکیده
منابع مشابه
Determination of Arabidopsis thaliana telomere length by PCR
In humans, telomere length studies have acquired great relevance because the length of telomeres has been related to natural processes like disease, aging and cancer. However, very little is known about the influence of telomere length on the biology of wild type plants. The length of plant telomeres has been usually studied by Terminal Restriction Fragment (TRF) analyses. This technique requir...
متن کاملCorrigendum: Determination of Arabidopsis thaliana telomere length by PCR
This Article contains a typographical error in the Methods section under the subheading 'MMQPCR amplifica-tion' , where " 4 × 1.5 μ L each primer 10 mM (TelA, TelB and the pair of primers used to amplify CYP5) " should read: " 4 × 1.5 μ L each primer 10 μ M (TelA, TelB and the pair of primers used to amplify CYP5) ". This work is licensed under a Creative Commons Attribution-NonCommercial-NoDer...
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Telomeres have the paradoxical ability of protecting linear chromosome ends from DNA damage sensors by using these same proteins as essential components of their maintenance machinery. We have previously shown that the absence of ataxia telangiectasia mutated (ATM), a central regulator of the DNA damage response, accelerates the onset of genome instability in telomerase-deficient Arabidopsis, w...
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TRF2, a component of the shelterin complex, functions to protect telomeres. TRF2 contains an N-terminal basic domain rich in glycines and arginines, similar to the GAR motif that is methylated by protein arginine methyltransferases. However, whether arginine methylation regulates TRF2 function has not been determined. Here we report that amino acid substitutions of arginines with lysines in the...
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Telomeres, nucleoprotein structures at the ends of linear eukaryotic chromosomes, are important for the maintenance of genomic stability. Telomeres were considered as typical heterochromatic regions, but in light of recent results, this view should be reconsidered. Asymmetrically located cytosines in plant telomeric DNA repeats may be substrates for a DNA methyltransferase enzyme and indeed, it...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2007
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.02059-06