Technetium-99m antimyosin imaging in a canine infarct model

Technetium-99m tricarbonyl labeled a broad-spectrum quinolone as a specific imaging agent in infection diseases

Nuclear medicine imaging has been used to localize infection sites and efforts have been continued to develop modified infection specific radiopharmaceuticals. In this study gemifloxacin as a broad-spectrum quinolone has been labeled with [99mTc (CO)3 (H2O)3]+ core in order to evaluate its feasibility as an infection imaging agent for in vivo use. The stability of radioconjugate was checked in ...

Myocardial infarct imaging using 99m technetium pyrophosphate and 99mtechnetium methylene diphosphonate: a clinical evaluation.

THE use of radionuclides in elucidating ischaemic heart disease is a recent development. Since Bonte et al. (1974) first described the concentration of 99mTechnetium labelled phosphates in acutely damaged myocardium numerous radiopharmaceuticals, techniques, experience and data have accumulated in the non-invasive imaging methods for the direct visualisation of acute myocardial infarction. The ...

Technetium-99m tricarbonyl labeled a broad-spectrum quinolone as a specific imaging agent in infection diseases

Nuclear medicine imaging has been used to localize infection sites and efforts have been continued to develop modified infection specific radiopharmaceuticals. In this study gemifloxacin as a broad-spectrum quinolone has been labeled with [99mTc (CO)3 (H2O)3]+ core in order to evaluate its feasibility as an infection imaging agent for in vivo use. The stability of radioconjugate was checked in ...

Present status of the 99m technetium pyrophosphate infarct scintigram.

PRELIMINARY STUDIES OF TECHNETIUM-99m-LABELED ANTIMYOSIN MONOCLONAL ANTIBODY: DEVELOPMENT OF RADIOPHARMACEUTICAL FOR CARDIAC EVALUATION

In the acute myocardium infarction, the myocytes cell membrane loses its integrity, allowing the influx of extracellular macromolecules such as circulating antibody into the damaged cell. Specific antibodies to cardiac myosin can therefore bind to the acutely necrotic myocyte, allowing the noninvasive localization and dimension of myocardial infarction. Because of its favorable physical charact...