منابع مشابه
Logical Decision Rules: Teaching C4.5 to Speak Prolog
It is desirable to automatically learn the effects of actions in an unknown environment. C4.5 has been used to discover associations, and it can also be used to find causal rules. Its output consists of rules that predict the value of a decision attribute using some condition attributes. Integrating C4.5's results in other applications usually requires spending some effort in translating them i...
متن کاملProtein conducting nanopores.
About 50% of the cellular proteins have to be transported into or across cellular membranes. This transport is an essential step in the protein biosynthesis. In eukaryotic cells secretory proteins are transported into the endoplasmic reticulum before they are transported in vesicles to the plasma membrane. Almost all proteins of the endosymbiotic organelles chloroplasts and mitochondria are syn...
متن کاملMonitoring protein adsorption with solid-state nanopores.
Solid-state nanopores have been used to perform measurements at the single-molecule level to examine the local structure and flexibility of nucleic acids, the unfolding of proteins, and binding affinity of different ligands. By coupling these nanopores to the resistive-pulse technique, such measurements can be done under a wide variety of conditions and without the need for labeling. In the res...
متن کاملSpeak to me, melody
Music, more than any other art form, can raise the human spirit to the heights of joy or plunge it into the depths of sorrow. Yet, the power of music to influence our emotions, regardless of age or cultural background, has left philos ophers, scholars and musicians baffled; perhaps unsurprisingly, given the inevitable subject ivity of the phenomenon (Fig 1). In the late twentieth century, biolo...
متن کاملProtein Detection by Nanopores Equipped with Aptamers
Protein nanopores have been used as stochastic sensors for the detection of analytes that range from small molecules to proteins. In this approach, individual analyte molecules modulate the ionic current flowing through a single nanopore. Here, a new type of stochastic sensor based on an αHL pore modified with an aptamer is described. The aptamer is bound to the pore by hybridization to an olig...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Methods
سال: 2016
ISSN: 1548-7091,1548-7105
DOI: 10.1038/nmeth.3988