Tau modulates visual plasticity in adult and old mice
نویسندگان
چکیده
منابع مشابه
Adult Visual Cortical Plasticity
The visual cortex has the capacity for experience-dependent change, or cortical plasticity, that is retained throughout life. Plasticity is invoked for encoding information during perceptual learning, by internally representing the regularities of the visual environment, which is useful for facilitating intermediate-level vision--contour integration and surface segmentation. The same mechanisms...
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The scarce functional recovery of the adult CNS following injuries or diseases is largely due to its reduced potential for plasticity, the ability to reorganize neural connections as a function of experience. Recently, some new strategies restoring high levels of plasticity in the adult brain have been identified, especially in the paradigmatic model of the visual system. A chronic treatment wi...
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BACKGROUND Early life trauma is an important risk factor for many psychiatric and somatic disorders in adulthood. As a growing body of evidence suggests that brain plasticity is disturbed in affective disorders, we examined the short-term and remote effects of early life stress on different forms of brain plasticity. METHODOLOGY/PRINCIPAL FINDINGS Mice were subjected to early deprivation by i...
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PURPOSE Little is known about neuronal changes during ageing in the visual system of mice which are increasingly being used as animal models for human visual disorders. METHODS AND RESULTS Measuring the optomotor response to moving gratings, visual acuity of C57BL/6-mice was 0.39 cycles/degree (cyc/deg) until 12 months of age and declined to 0.27 cyc/deg (by 30%) at 26 months. In the visual w...
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Plasticity appears to be a ubiquitous property of nervous systems, regardless of developmental stage or complexity. In the visual system of higher mammals, perceptual plasticity has been intensively studied, both during development and in adulthood. However, the last few years have seen some significant controversies arise about the existence and properties of visual plasticity after permanent ...
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ژورنال
عنوان ژورنال: Neurobiology of Aging
سال: 2020
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2020.07.024