Taste Receptors in the Gastrointestinal Tract. V. Acid sensing in the gastrointestinal tract
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منابع مشابه
Taste receptors in the gastrointestinal tract. V. Acid sensing in the gastrointestinal tract.
Luminal acidity is a physiological challenge in the foregut, and acidosis can occur throughout the gastrointestinal tract as a result of inflammation or ischemia. These conditions are surveyed by an elaborate network of acid-governed mechanisms to maintain homeostasis. Deviations from physiological values of extracellular pH are monitored by multiple acid sensors expressed by epithelial cells a...
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of the gastrointestinal tract modulate gastrointestinal functions, including absorption of nutrients, food intake and protection against harmful substances. The current notion is that mucosal enteroendocrine cells act as primary chemoreceptors by releasing signaling molecules in response to changes in the luminal environment, which in turn activate nerve terminals. The recent discovery that tas...
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Changes in the luminal contents of the gastrointestinal tract modulate gastrointestinal functions, including absorption of nutrients, food intake, and protection against harmful substances. The current notion is that mucosal enteroendocrine cells act as primary chemoreceptors by releasing signaling molecules in response to changes in the luminal environment, which in turn activate nerve termina...
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Correspondence Peter Holzer, Ph.D., Professor, Research Unit of Translational Neurogastroenterology, Department of Experimental and Clinical Pharmacology, Medical University of Graz, Universitätsplatz 4, A8010 Graz, Austria. Tel: +43-316-3804500; Fax: +43-316-3809645; E-mail: [email protected] Page 1 of 26 Articles in PresS. Am J Physiol Gastrointest Liver Physiol (November 22, 2006). ...
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The extracellular calcium-sensing receptor (CaR) is a multimodal sensor for several key nutrients, notably Ca2+ ions and L-amino acids, and is expressed abundantly throughout the gastrointestinal tract. While its role as a Ca2+ ion sensor is well recognized, its physiological significance as an L-amino acid sensor and thus, in the gastrointestinal tract, as a sensor of protein ingestion is only...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Gastrointestinal and Liver Physiology
سال: 2007
ISSN: 0193-1857,1522-1547
DOI: 10.1152/ajpgi.00517.2006