TASSER_low-zsc: An approach to improve structure prediction using low z-score-ranked templates

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TASSER_low-zsc: an approach to improve structure prediction using low z-score-ranked templates.

In a variety of threading methods, often poorly ranked (low z-score) templates have good alignments. Here, a new method, TASSER_low-zsc that identifies these low z-score-ranked templates to improve protein structure prediction accuracy, is described. The approach consists of clustering of threading templates by affinity propagation on the basis of structural similarity (thread_cluster) followed...

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ژورنال

عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics

سال: 2010

ISSN: 0887-3585

DOI: 10.1002/prot.22791