Targeting of 111In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells
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چکیده
منابع مشابه
Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells.
PURPOSE Anticancer dendritic cell (DC) vaccines require the DCs to relocate to lymph nodes (LN) to trigger immune responses. However, these migration rates are typically very poor. Improving the targeting of ex vivo generated DCs to LNs might increase vaccine efficacy and reduce costs. We investigated DC migration in vivo in humans under different conditions. EXPERIMENTAL DESIGN HLA-A*02:01 p...
متن کاملTargeting of In-Labeled Dendritic Cell Human Vaccines Improved by Reducing Number of Cells
Purpose: Anticancer dendritic cell (DC) vaccines require the DCs to relocate to lymph nodes (LN) to trigger immune responses.However, thesemigration rates are typically very poor. Improving the targeting of ex vivo generatedDCs to LNsmight increase vaccine efficacy and reduce costs.We investigatedDCmigration in vivo in humans under different conditions. Experimental Design:HLA-A 02:01 patients ...
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Purpose: Anticancer dendritic cell (DC) vaccines require the DCs to relocate to lymph nodes (LN) to trigger immune responses.However, thesemigration rates are typically very poor. Improving the targeting of ex vivo generatedDCs to LNsmight increase vaccine efficacy and reduce costs.We investigatedDCmigration in vivo in humans under different conditions. Experimental Design:HLA-A 02:01 patients ...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2013
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-12-1879