Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth
نویسندگان
چکیده
منابع مشابه
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.
PURPOSE Various studies have shown the importance of the GAIP interacting protein, COOH-terminus (GIPC, also known as Synectin) as a central adaptor molecule in different signaling pathways and as an important mediator of receptor stability. GIPC/Synectin is associated with different growth-promoting receptors such as insulin-like growth factor receptor I (IGF-IR) and integrins. These interacti...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2009
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-08-2837