Targeting chromatin remodelling proteins to treat pancreatic cancer
نویسندگان
چکیده
منابع مشابه
Targeting the hypoxia pathway to treat pancreatic cancer
The correlation between hypoxia and pancreatic cancer has long been discussed. Hao's research team made many efforts on revealing the oncogenic function of hypoxic inducible factor-1 (HIF-1) in pancreatic cancer progression and development in recent years. Based on their research, they linked micro-environmental regulation of pancreatic cancer and its clinical significance. Hao's research team ...
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Sattva S. Neelapu and Padmanee Sharma Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; Center for Cancer Immunology Research, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030; and Department of Immunology...
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Pancreatic cancer (PC) is the fourth leading cause of cancer related-deaths in both men and women, and the 1- and 5-year relative survival rates are 25% and 6%, respectively. It is known that smoking, alcoholism and psychological stress are risk factors that can promote PC and increase PC progression. To date, the prevention of PC is crucial because there is no curative treatment. After binding...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2015
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2015.171