منابع مشابه
Targeted cancer therapy: review article
Cancer is one of the most dangerous health problems of today modern societies which has an increasing rate especially in developing countries. There are many diverse ongoing treatment attempts trying to defeat cancer. Despite that, scientists have been unable to find a permanent cure for this disease. In many cases although there is a successful first response in patients, cancer cells are fina...
متن کاملTargeted therapy for lung cancer.
To meet that challenge, an action plan [2] was designed by the European Respiratory Society (ERS) Thoracic Oncology Assembly officers in March 2010, which was subsequently approved and strongly welcomed by the ERS Executive Committee. Today the Thoracic Oncology Assembly has almost achieved all of the following. 1) To create a Task Force for a European initiative for quality management in lung ...
متن کاملPersonalized Targeted Therapy for Lung Cancer
Lung cancer has long been recognized as an extremely heterogeneous disease, since its development is unique in every patient in terms of clinical characterizations, prognosis, response and tolerance to treatment. Personalized medicine refers to the use of markers to predict which patient will most likely benefit from a treatment. In lung cancer, the well-developed epidermal growth factor recept...
متن کاملSuccesses and limitations of targeted cancer therapy in lung cancer.
Human cancers usually evolve through multistep processes. These processes are driven by the accumulation of abundant genetic and epigenetic abnormalities. However, some lung cancers depend on a single activated oncogene by somatic mutation, termed 'driver oncogenic mutations', for their proliferation and survival. EGFR(epidermal growth factor receptor) mutations and ALK(anaplastic lymphoma kina...
متن کاملLung Cancer: Targets and Therapy MET targeted therapy for lung cancer: clinical development and future directions
Correspondence: Patrick C Ma Cleveland Clinic Taussig Cancer Institute, 9500 Euclid Avenue, R40, Cleveland, OH 44195, USA Tel +1 216 445 5545 Fax +1 216 636 2498 Email [email protected] Abstract: MET, the receptor for hepatocyte growth factor, has been identified as a novel promising target in various human malignancies, including lung cancer. Research studies have demonstrated that MET signaling pla...
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ژورنال
عنوان ژورنال: Journal of the Korean Medical Association
سال: 2008
ISSN: 1975-8456
DOI: 10.5124/jkma.2008.51.5.483