Targeted inhibition of EG-1 blocks breast tumor growth
نویسندگان
چکیده
منابع مشابه
Small interfering RNA targeted to secretory clusterin blocks tumor growth, motility, and invasion in breast cancer.
Clusterin/apolipoprotein J (Clu) is a ubiquitously expressed secreted heterodimeric glycoprotein that is implicated in several physiological processes. It has been reported that the elevated level of secreted clusterin (sClu) protein is associated with poor survival in breast cancer patients and can induce metastasis in rodent models. In this study, we investigated the effects of sClu inhibitio...
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ژورنال
عنوان ژورنال: Cancer Biology & Therapy
سال: 2007
ISSN: 1538-4047,1555-8576
DOI: 10.4161/cbt.6.6.4189