Tapentadol for chronic musculoskeletal pain in adults
نویسندگان
چکیده
منابع مشابه
Lasting Prolonged-Release Tapentadol for Moderate/Severe Non-Cancer Musculoskeletal Chronic Pain
INTRODUCTION Despite opioids' recognized role in the treatment of moderate/severe musculoskeletal chronic pain, their long-term benefits need investigation. We explored the lasting analgesic efficacy, tolerability, influence on life quality, and chronicity stage of the novel prolonged release (PR) opioid, tapentadol, in 30 outpatients. METHODS We evaluated patients' pain intensity and relief ...
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Tapentadol is a centrally acting analgesic with a dual mechanism of action of mu receptor agonism and norepinephrine reuptake inhibition. Tapentadol immediate-release is approved by the US Food and Drug Administration for the management of moderate-to-severe acute pain. It was developed to decrease the intolerability issue associated with opioids. Tapentadol extended-release has a 12-hour durat...
متن کاملTapentadol extended release for the management of chronic neck pain
BACKGROUND The role of opioids in the management of chronic neck pain is still poorly investigated. No data are available on tapentadol extended release (ER). In this article, we present 54 patients with moderate-to-severe chronic neck pain treated with tapentadol ER. PATIENTS AND METHODS Patients received tapentadol ER 100 mg/day; dosage was then adjusted according to clinical needs. The fol...
متن کاملSystematic review of tapentadol in chronic severe pain.
AIM A systematic review of chronic pain treatment with strong opioids (step 3 WHO pain ladder) and a comparison to a new drug recently approved for the treatment of severe chronic pain in Europe, tapentadol (Palexia, Nucynta*), were performed. METHODS Thirteen electronic databases were searched as well as a number of other sources from 1980 up to November 2010 for relevant randomized controll...
متن کاملPrediction of response to tapentadol in chronic low back pain
BACKGROUND Many chronic low back pain (cLBP) patients do not satisfactorily respond to treatment. The knowledge of responders and non-responders before initiating treatment would improve decision making and reduce health care costs. The aims of this exploratory prediction study in cLBP patients treated with tapentadol were to identify predictors of treatment outcome based on baseline characteri...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2015
ISSN: 1465-1858
DOI: 10.1002/14651858.cd009923.pub2