Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue
نویسندگان
چکیده
منابع مشابه
Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue.
Cancer patients frequently suffer from fatigue, a complex syndrome associated with tiredness and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, escalates during treatment, and can persist for years after treatment. CRF negatively influences quality of life, limits functional independence, and is associated with decreased survival in patients with incurable...
متن کاملRegarding cancer-related fatigue.
This is in response to the article “Cancer-related fatigue: a review”, published in April 2011 by Campos et al.1. We have a few concerns regarding certain statements made by the authors. The advances in oncology have rendered cancer from a universally lethal disease to a chronic condition for many and a curable illness for a few. Hence, the potential long-term adverse effects of supportive care...
متن کاملPhysical Behavior Profiles in Chronic Cancer-Related Fatigue
PURPOSE Increasing physical activity level is a generally effective intervention goal for patients who suffer from chronic cancer-related fatigue (CCRF). However, patients are unlikely to benefit equally from these interventions, as their behavioral starting points might vary substantially. Therefore, we explored patterns of physical behavior of participants who suffer from CCRF. METHODS Base...
متن کاملMechanisms of cancer-related fatigue.
Cancer-related fatigue (CRF) is one of the most prevalent symptoms patients with cancer experience, both during and after treatment. CRF is pervasive and affects patients' quality of life considerably. It is important, therefore, to understand the underlying pathophysiology of CRF in order to develop useful strategies for prevention and treatment. At present, the etiology of CRF is poorly under...
متن کاملPathophysiology of cancer-related fatigue.
Cancer-related fatigue (CRF) is influenced and modulated by a number of critical factors, and the mechanism that is both necessary and sufficient to induce development of severe fatigue in patients with cancer has not yet been identified. Specific research efforts to understand the factors that may contribute to CRF development have been made, including studies of the direct effects of tumor bu...
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ژورنال
عنوان ژورنال: Pharmacological Research
سال: 2017
ISSN: 1043-6618
DOI: 10.1016/j.phrs.2017.07.012