منابع مشابه
Tales from the crypt
Tales from the crypt ow many stem cells reside in a human colonic crypt and how do they divide and regenerate? According to the deterministic theory, a small number of " immortal " stem cells haunt a crypt, and when they divide, each generates a single replacement stem cell. The stochastic model, in contrast, contends that a crypt niche harbors many stem cells, and each cell division randomly g...
متن کاملTales from the Crypt
Mathematical modeling is being increasingly recognized within the biomedical sciences as an important tool that can aid the understanding of biological systems. The heavily regulated cell renewal cycle in the colonic crypt provides a good example of how modeling can be used to find out key features of the system kinetics, and help to explain both the breakdown of homeostasis and the initiation ...
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The enterocyte is a highly specialized cell of the duodenal epithelium that coordinates iron uptake and transport into the body. Until recently, the molecular mechanisms underlying iron absorption and iron homeostasis have remained a mystery. This review focuses on the proteins and regulatory mechanisms known to be present in the enterocyte precursor cell and in the mature enterocyte. The recen...
متن کاملTales from the crypt: a parasitoid manipulates the behaviour of its parasite host
There are many examples of apparent manipulation of host phenotype by parasites, yet few examples of hypermanipulation-where a phenotype-manipulating parasite is itself manipulated by a parasite. Moreover, few studies confirm manipulation is occurring by quantifying whether the host's changed phenotype increases parasite fitness. Here we describe a novel case of hypermanipulation, in which the ...
متن کاملAlien vs. Quine, the Vanishing Circuit and Other Tales from the Industry's Crypt
In this talk we will illustrate the everyday challenges met by embedded security practitioners by five real examples. All the examples were actually encountered while designing, developing or evaluating commercial products. This note, which is not a refereed research paper, presents the details of one of these five examples. It is intended to help the audience follow that part of our presentation.
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2001
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1546rr2