Tachyzoites of toxoplasma gondii in cerebrospinal fluid: A rare finding
نویسندگان
چکیده
منابع مشابه
Toxoplasma gondii in cerebrospinal fluid.
Editor, Toxoplasma gondii is a rare cause of meningitis. Here we report a case of one year old child who presented with low grade fever and fits. Physical examination was essentially normal. His haemoglobin was 13.2G%. Total and differential leucocyte counts and ESR were normal. Blood smear was negative for malarial parasite and both views of x.ray skull were also normal. A lumbar puncture was ...
متن کاملAcidocalcisomes in Toxoplasma gondii tachyzoites.
Toxoplasma gondii tachyzoites were loaded with the fluorescent indicator fura 2 to investigate the transport mechanisms involved in maintaining their intracellular Ca2+ homoeostasis. The mitochondrial ATPase inhibitor oligomycin and the endoplasmic-reticulum Ca(2+)-ATPase inhibitor thapsigargin increased the intracellular Ca2+ concentration ([Ca2+]i), thus indicating the requirement for ATP and...
متن کاملImmunogenicity of Gamma-Irradiated Toxoplasma gondii Tachyzoites in Mice
The Immunogenicity of γ-irradiated tachyzoites of a highly virulent strain of Toxoplasma gondii (RH strain) was investigated. Immunized mice survived challenge infection and displayed increased interferon gamma (INF-γ ) production. On the other hand, nonimmunized controls died after 10 days and displayed a significantly decreased lymphoproliferative response to Concanavalin A (Con A). No tachyz...
متن کاملIdentification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites
Drug treatment for toxoplasmosis is problematic, because current drugs cannot eradicate latent infection with Toxoplasma gondii and can cause bone marrow toxicity. Because latent infection remains after treatment, relapse of infection is a problem in both infections in immunocompromised patients and in congenitally infected patients. To identify lead compounds for novel drugs against Toxoplasma...
متن کاملTriazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo.
The triazine WR99210 [4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(2,4,5-trichlorophenoxypropyloxy)-1,3,5 triazine] inhibits Toxoplasma gondii in vitro at nanomolar levels (P < 0.05). The 50% inhibitory concentration (IC(50)) was approximately 50 nM. It is a potent inhibitor in vitro and is also effective in vivo. Administration of WR99210 parenterally (i.e., intraperitoneally) reduced the mean numb...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cytology
سال: 2020
ISSN: 0970-9371
DOI: 10.4103/joc.joc_65_19