t(4;12)(q11-q21;p13)

Granuloblastic sarcoma: onset with cutaneous polymorphic lesions.

A 54 year-old-woman developed papulo-erythematous lesions on her face, arms, and trunk .These lesions showed polymorphic features. (Figure 1) Biopsy revealed an extramedullary (cutaneous and subcutaneous) infiltration of poorly differentiated myeloid cells CD34+, CD68+, LYSOZIME+, MPO+, CAE-, CD3-.(Figure 2-3) The bone marrow aspiration was compatible with chronic myelomonocytic leukemia with n...