T-Wave Alternans, Restitution of Human Action Potential Duration, and Outcome
نویسندگان
چکیده
منابع مشابه
T-wave alternans, restitution of human action potential duration, and outcome.
OBJECTIVES Our aim was to study the relationship between T-wave alternans (TWA) and rate-response (restitution) of repolarization in subjects with and without ventricular systolic dysfunction. BACKGROUND T-wave alternans is a promising predictor of sudden death, yet the mechanisms linking it with human ventricular arrhythmias are unclear. From theoretic considerations, we hypothesized that ab...
متن کاملHuman ventricular action potential duration restitution.
. Brugada P, Brugada J. Right bundle branch block, persistent ST segment elevation and sudden death: a distinct clinical and electrocardiographic syndrome. J Am Coll Cardiol 1992;20:1391–6. . Yan GX, Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 1999;100:1660–6. . Breithardt G, Cain ME, El-Sheri...
متن کاملDynamic restitution of action potential duration during electrical alternans and ventricular fibrillation.
The restitution kinetics of action potential duration (APD) were investigated in paced canine Purkinje fibers (P; n = 9) and endocardial muscle (M; n = 9), in isolated, perfused canine left ventricles during ventricular fibrillation (VF; n = 4), and in endocardial muscle paced at VF cycle lengths (simulated VF; n = 4). Restitution was assessed with the use of two protocols: delivery of a single...
متن کاملAction potential duration restitution kinetics in human atrial fibrillation.
OBJECTIVES We undertook this study to determine whether human atrial fibrillation (AF) relates to steeply sloped action potential duration restitution (APDR) kinetics and whether the spatial nonuniformity of APDR promotes persistence of AF. BACKGROUND A steeply sloped APDR curve is known to be an important determinant of the induction of more complex action potential duration (APD) dynamics a...
متن کاملSimulation of T-Wave Alternans and its Relation to the Duration of Ventricular Action Potentials Disturbance
The aim of the study was to simulate T-wave alternans (TWA) magnitude distribution maps on the body surface employing ECGSIM program and then to compare obtained results with data measured from patients. The toolbox for ECGSIM program was developed for TWA simulation. Graphical representation of spatial distribution of TWA magnitude was implemented. Body surface maps of TWA were simulated for d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2007
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2007.10.011