T cell Metabolism–Regulating Energy

Energy Metabolism and T-cell-mediated Cytolysis

The destruction of appropriate target cells by cytolytic thymus-derived lymphocytes (CTL) 1 is an active energy-requiring phenomenon (1-3). In the accompanying paper (4), we presented evidence that T-cell-mediated cytolysis could be supported by either oxidative or glycolytic energy pathways and was in general strongly inhibited only in those situations in which both respiration and glycolysis ...

Activation Metabolism during Effector T Cell Macroautophagy Regulates Energy

Peripheral T-cell Lymphoma of the Uvula: A Rare Entity

Abstract Introduction: Extra-nodal exposition of T-cell non-hodgkin lymphoma (NHL) is extremely rare, and is frequently observed in patients with immune system dysfunction. Peripheral T-cell lymphoma does not express CD56 is rare. Malignant lymphoma of the uvula is exceedingly unusual. The current study reported a case of peripheral T-cell lymphoma of the uvula in an immunecompetent patient. ...

Hypocalcemia Revealing an Enteropathy-Associated T-cell Lymphoma

Background: Neurofollicular hamartoma (NFH) is characterized histopathologically by fascicles of spindle cells that laterally delimited by hyperplastic folliculosebaceous units. It usually appears on face, near the nose or nasolabial fold. It does not manifest true neural differentiation and recently the term spindle cell predominant trichodiscoma (SCPT) has been used instead. Case Presentatio...

Specific cutaneous manifestations in adult T cell leukemia/lymphoma

Background and aim: Adult T cell leukemia/lymphoma (ATLL) is an aggresive malignancy which may occur in human T lymphotropic virus1(HTLV1) infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad.Mate...