Systemic sclerosis and autoimmune hepatitis
نویسندگان
چکیده
منابع مشابه
Autoimmune hepatitis and systemic sclerosis: a new overlap syndrome?
OBJECTIVE We report the cases of two patients with the complete CREST variant (calcinosis, Raynaud's phenomenon, oesophageal dysmotility, sclerodactyly, telangiectasia) of systemic sclerosis (SSc) who developed autoimmune hepatitis. RESULTS Our findings suggest that autoimmune hepatitis can be considered to be one of the liver manifestations associated with SSc. Our data also indicate that, b...
متن کاملAutoimmune hepatitis
Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...
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Autoimmune hepatitis (AIH) is a chronic disorder characterized by persistent hepatocellular inflammation and necrosis. AIH overlap syndromes with other autoimmune diseases have been reported, including connective tissue diseases (CTD). Reports of AIH in systemic sclerosis (SSc), however, are scarce and have been particularly described in the limited SSc subtype. We report a case of systemic scl...
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We report a series of five patients with autoimmune hepatitis (AIH) accompanied by systemic lupus erythematosus (SLE) (AIH-SLE overlap). Serologic tests showed that all patients were positive for antinuclear antibody and double-stranded DNA antibody. Histological examination of the liver showed that three of the patients had chronic hepatitis with severe activity. One of the other two had acute...
متن کاملdevelopment of systemic sclerosis in patients with autoimmune hepatitis: an emerging overlap syndrome
aim : we described two case reports of aih/ssc overlap syndrome and reviewed literatures regarding this issue. background : aih is a chronic hepatitis of unknown aetiology characterized by continuing hepatocellular necrosis and inflammation. aih overlap syndromes have been reported with other autoimmune diseases. patients and methods : according to the classification criteria for ssc, we cond...
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ژورنال
عنوان ژورنال: Clinical Rheumatology
سال: 2010
ISSN: 0770-3198,1434-9949
DOI: 10.1007/s10067-010-1440-4