Systemic EBV-Positive Methotrexate-Related Lymphoproliferative Disorder Associated With Skin Lesion Resembling EBV-Positive Mucocutaneous Ulcer
نویسندگان
چکیده
منابع مشابه
EBV-positive mucocutaneous ulcer of the oral cavity associated with HIV/AIDS.
OBJECTIVE To present 2 cases of Epstein-Barr virus (EBV)-positive mucocutaneous ulcer of the oral mucosa in association with human immunodeficiency virus infection. STUDY DESIGN Two recently diagnosed cases of EBV-positive mucocutaneous ulcer of the oral mucosa in patients with human immunodeficiency virus (HIV) were reviewed with regard to their clinical, histomorphologic, and immunophenotyp...
متن کاملThe ambiguous boundary between EBV-related hemophagocytic lymphohistiocytosis and systemic EBV-driven T cell lymphoproliferative disorder.
Epstein Barr virus (EBV)-related hemophagocytic lymphohistiocytosis (EBV-HLH) is a form of acquired, infection-related HLH which typically represents a fulminant presentation of an acute EBV infection of CD8+ T cells with 30-50% mortality rate. Systemic EBV-positive lymphoproliferative disease of childhood (SE-LPD) is a rare T cell lymphoproliferative disorder predominantly arising in the setti...
متن کامل[Senile EBV-associated B-cell lymphoproliferative disorder].
Epstein-Barrvirus (EBV)は1964年 にアフリカのバー キットリンパ腫培養細胞から発見された.そ の後,上 咽頭 がんや 胃がんなどとの関わ りも明らかにされ,歴 史的に最 も活発 に研究 がな されて きた ヒ トがん ウイルスhuman Cancer virusで あると言える.そ の明 らかな発癌 との関連 にも関わらず,EBVは 高度に普遍的なウイルスで もある. EBVは 主に唾液 を関した母子感染によって伝播 されると 考えられる.わ が国の25歳 以上の成人人口においては,ほ ぼ100%に 近い感染率を示す とされる. EBVと 血 液 リ ンパ 系 疾 患 との 関 わ りは 深 い.表1に, 主 なEBV関 連 血 液 リ ンパ 系 疾 患 を示 す.知 られ る 限 り リ ンパ 系 疾 患 が 主 体 で あ り,顆 粒 球 系 な ど他 ...
متن کاملKSHV- and EBV-associated germinotropic lymphoproliferative disorder.
Kaposi sarcoma-associated herpesvirus (KSHV) is known to be associated with 3 distinct lymphoproliferative disorders: primary effusion lymphoma (PEL), multicentric Castleman disease (MCD), and MCD-associated plasmablastic lymphoma. We report 3 cases of a previously undescribed KSHV-associated lymphoproliferative disorder. The disease presented as localized lymphadenopathy and showed a favorable...
متن کاملCase-report: EBV driven lymphoproliferative disorder associated with Ruxolitinib
BACKGROUND Ruxolitinib, a novel inhibitor of Janus kinases 1 and 2, was recently approved for the treatment of myelofibrosis but, recently, attention has been drawn to potential side effects and especially opportunistic infections and virus reactivations. EBV reactivation has not previously been reported to occur in association with Ruxolitinib. CASE PRESENTATION We report a case of a 57 year...
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ژورنال
عنوان ژورنال: The American Journal of Dermatopathology
سال: 2021
ISSN: 0193-1091
DOI: 10.1097/dad.0000000000001930