Systemic complement activation levels in Stargardt disease
نویسندگان
چکیده
منابع مشابه
Systemic complement activation in central serous chorioretinopathy
PURPOSE A clear link between several variants in genes involved in the complement system and chronic central serous chorioretinopathy (CSC) has been described. In age-related macular degeneration, a disease that shows clinical features that overlap with CSC, both genetic risk factors and systemic activation of the complement system have previously been found. In this case-control study, we asse...
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Purpose Primary visual cortex (PVC) contains a retinotopic map in which the central visual field (CVF) is highly magnified compared to the peripheral field. Several studies have used functional magnetic resonance imaging (fMRI) in patients with macular degeneration to assess the reorganization of visual processing in relationship with the development of extrafoveal preferred retinal locus (PRL)...
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Complement is an acute-reacting non-specific effector system. Activation and consumption of individual components of this multicomponent system occur secondarily to specific complement fixing events. The complement system is therefore an indirect and imprecise diagnostic tool and can be used clinically only as a general indicator of the severity of a particular disease or as a monitor of its pr...
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OBJECTIVE To demonstrate that Stargardt disease (STGD) can present with peripapillary atrophy. METHODS Retrospective case series. The medical records of 150 consecutive patients (300 eyes) were reviewed retrospectively from a STGD database from January 1999 to May 2007 at Columbia University's Harkness Eye Institute. STGD patients demonstrating peripapillary atrophy were identified. RESULTS...
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1 Prior P, Symmons D P M, Hawkins C F, Scott D L, Brown R. Cancer morbidity in rheumatoid arthritis. Ann Rheum Dis 1984; 43: 128-31. 2 Symmons D P M, Ahern M, Bacon P A, et al. Lymphoproliferative malignancy in rheumatoid arthritis: a study of 20 cases. Ann Rheum Dis 1984; 43: 132-5. 3 Isaacson P, Wright D H. Coeliac discase and malignant histiocytosis of the intestine. In: Whitehouse J M A, Wi...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2021
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0253716