Synthetic Micro/Nanomotors for Drug Delivery
نویسندگان
چکیده
Synthetic micro/nanomotors (MNMs) are human-made machines characterized by their capacity for undergoing self-propelled motion as a result of the consumption chemical energy obtained from specific or biochemical reactions, response to an external actuation driven physical stimulus. This has fostered exploitation MNMs facing different biomedical challenges, including drug delivery. In fact, superior systems efficient delivery drugs, offering several advantages in relation conventional carriers. For instance, self-propulsion ability makes possible easier transport drugs targets comparison distribution passive carriers circulating within blood, which enhances bioavailability tissues. Despite promising avenues opened use synthetic applications, development vivo uses requires further studies ensure suitable biocompatibility and biodegradability fabricated engines. is essential guaranteeing safety patient convenience. review provides updated perspective potential applications Moreover, most fundamental aspects related performance biosafety also discussed.
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1Nano Medical Engineering Laboratory, RIKEN, Wako-shi, Saitama 351-0198, Japan 2Department of Environmental Chemistry and Engineering, Graduate School of Interdisciplinary Science and Engineering, Tokyo Institute of Technology, Yokohama-shi, Kanagawa 226-8502, Japan 3Department of Biomedical Engineering, Faculty of Engineering, National University of Singapore, Singapore 117602 4Department of B...
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ژورنال
عنوان ژورنال: Technologies (Basel)
سال: 2022
ISSN: ['2227-7080']
DOI: https://doi.org/10.3390/technologies10040096